Cleveland Clinic Mastering the Management of Aortic Valve Disease 2025

* WARNING: This is the full version, not the incomplete one that many other websites are selling cheaply.
The management of patients with aortic valve disease is constantly evolving, highlighted by innovations in devices, surgical techniques and imaging. In addition, research studies and clinical trials are continually expanding the evidence base related to management decisions and interventions. This educational activity will offer a comprehensive platform for healthcare professionals to explore the latest evidence-based practices, procedural techniques, and collaborative strategies critical for managing patients with aortic valve disease.
Who Should Attend?
This course is intended for cardiologists, cardiology fellows, cardiothoracic surgeons, internists, nurses, physician assistants, and all health care professionals involved in the evaluation, diagnosis and/or management of patients with aortic valve disease.
Learning Objectives

Evaluate the clinical presentation and management strategies for patients with aortic valve disease by incorporating patient-specific considerations, timing of intervention and risk stratification.
Analyze the strengths and limitations of various imaging modalities for diagnosing and guiding the treatment of aortic valve disease.
Describe the current state-of-the-art and emerging therapeutic options for aortic valve disease, emphasizing evidence-based and patient-centered care.
Incorporate interprofessional approaches to optimize outcomes for patients undergoing transcatheter and surgical interventions.
Navigate the management and ethical dilemmas in the management of elderly and medically complex patients with aortic valve disease.

+ Topics:

Friday, December 5, 2025
All times in Eastern Time

7:00 am

Registration & Continental Breakfast

7:50 am

Welcome & Announcements
Lars G. Svensson, MD, PhD

Session 1: A Contemporary Overview of Aortic Valve Disease in 2025
Moderators: Samir Kapadia, MD & Lars G. Svensson, MD, PhD

8:00 am

Contemporary trends in aortic valve disease management: Reflection on trial data & predictions for how the guidelines may evolve
Samir Kapadia, MD

8:15 am

Valvular heart disease in women: Implication for aortic valve therapies
Leslie Cho, MD

8:30 am

Evaluation of surgical & interventional risk: Key points for shared decision making
Patrick T. O’Gara, MD

8:45 am

Case Presentation: Low-risk severe AS in a 55-year-old
L. Leonardo Rodriguez, MD

8:50 am

Imaging cardiologist: Key clinical & multimodality imaging steps in work up & decision making
Milind Desai, MD, MBA

9:00 am

Surgical role: Current data to justify SAVR
Marijan Koprivanac, MD

9:10 am

Interventional: Current data to justify interventional, low risk TAVR trials: How do we use the new findings?
Jeffrey J. Popma, MD

9:30 am

Break & Exhibits

Session 2: Difficult Scenarios in Aortic Valve Disease Part 1
Moderators: Marijan Koprivanac, MD & Amar Krishnaswamy, MD

10:00 am

Case Presentation: Stenotic bicuspid aortic valve in an octogenarian
Christine Jellis, MD, PhD

10:05 am

Clinical Cardiologist: Assessing frailty & futility, multimodality imaging, concomitant aortopathy
Milind Desai, MD, MBA

10:15 am

Interventional: Association of BAV anatomy with TAVR outcomes
Samir Kapadia, MD

10:25 am

Surgeon: Role of surgery & contemporary outcomes
Marijan Koprivanac, MD

10:45 am

Case Presentation: Low flow – low gradient AS
Brian Griffin, MD

10:50 am

Cardiologist: (role of assessing flow reserve, aortic calcium scoring, small annulus, imaging/cath discordance) Image guidance technologies & the team approach to SHD interventions in the OR & Cath Lab
L. Leonardo Rodriguez, MD

11:00 am

Interventional Cardiologist: Current state of the art data PLUS echo/cath discordance
Grant Reed, MD

11:10 am

Surgeon: The benefit of surgical intervention in low flow, low gradient severe aortic stenosis
Marijan Koprivanac, MD

Session 3: Aortic Valve Endocarditis
Moderators: Leslie Cho, MD & Brian Griffin, MD

11:30 am

Case Presentation: Aortic valve endocarditis
L. Leonardo Rodriguez, MD

11:35 am

Clinical/Imaging Cardiologist: Role of multimodality imaging & clinical work up
Christine Jellis, MD, PhD

11:45 am

Critical care management of endocarditis
Leslie Cho, MD

11:55 am

Surgeon: What surgical options would I consider? (Including Ozaki)
Shinya Unai, MD

12:15 pm

Lunch

12:45 pm

Fireside Chat: Future of aortic valve treatment
Lars G. Svensson, MD, PhD and Patrick T. O’Gara, MD

Session 4: Difficult Scenarios in Aortic Valve Disease Part 2
Moderators: Christine Jellis, MD, MBA & L. Leonardo Rodriguez, MD

1:15 pm

Case Presentation: Radiation heart disease with aortic valve involvement
Christine Jellis, MD, PhD

1:20 pm

Clinical Cardiologist: Diagnosis & management
Milind Desai, MD, MBA

1:30 pm

Interventional options
Amar Krishnaswamy, MD

1:40 pm

Surgical options including TAVR explant
Shinya Unai, MD

Session 5: Aortic Valve and Connective Tissue Disorders
Moderators: Milind Desai, MD & Grant Reed, MD

2:00 pm

Case Presentation: Young patient with connective tissue disorder with enlarged aortic root: LDS vs. Marfan Syndrome
Brian Griffin, MD

2:05 pm

Clinical/Imaging: Work up of these patients: Current guidelines
Christine Jellis, MD, PhD

2:15 pm

Surgical management of the Aortic Root
Lars G. Svensson, MD, PhD

2:35 pm

Break & Exhibits

Session 6: Aortic Regurgitation in the Modern Era
Moderators: Lars G. Svensson, MD, PhD & Brian Griffin, MD

2:55 pm

Case Presentation – Patient with severe AI
Brian Griffin, MD

3:00 pm

Clinical/Imaging: Multimodality imaging work up & modern reappraisal of guidelines
Milind Desai, MD MBA

3:10 pm

Intervention: Treatment of AI using TAVR systems
Grant Reed, MD

3:20 pm

Surgeon: Aortic valve regurgitation including bicuspid valves: When to repair vs. Ross vs. replace with root management?
Lars G. Svensson, MD, PhD

Session 7: Management of Concomitant LVOT Obstruction (HOCM, subaortic membrane)
Moderators: Shinya Unai, MD & Milind Desai, MD, MBA

3:50 pm

Case Presentation – HOCM case with LVOT obstruction
Milind Desai, MD, MBA

3:55 pm

Cardiologist: Diagnosis & medical management
Milind Desai, MD, MBA

4:05 pm

Surgeon: Myectomy & membrane resection with concomitant AV
Shinya Unai, MD

4:15 pm

Interventional: Septal ablation (include suicide ventricle & need during interventional procedures)
Amar Krishnaswamy, MD

4:35 pm

Closing comments and adjourn to networking reception

Saturday, December 6, 2025
All times in Eastern Time

7:00 am

Breakfast

7:50 am

Welcome & Introduction

Session 1: New Data in Aortic Valve Diagnosis & Management Over the Last Two Years
Moderators: Samir Kapadia, MD & Grant Reed, MD

8:00 am

Most important TAVR papers 2024-24 (surgery versus TAVR data, bicuspid, EARLY TAVR type data, Moderate AS, Small annulus)
Grant Reed, MD

8:10 am

My most important contributions to TAVR from CC 2024-25
Samir Kapadia, MD

8:20 am

The most important surgical aortic valve papers from Cleveland Clinic
Marijan Koprivanac, MD

Session 2: The Crystal Ball: What will be the critical steps in management of aortic valve disease over next few years?
Moderators: Amar Krishnaswamy, MD & Grant Reed, MD

8:30 am

Clinical information & management: Beyond the Index Procedure – Upstream & downstream therapies
L. Leonardo Rodriguez, MD

8:40 am

Emerging medical therapies to slow progression of calcific AS
Milind Desai, MD MBA

8:50 am

Interventional techniques & trials (include importance of pre-emptive TAVR in the future management of AS, device durability challenges)
Jeffrey J. Popma, MD

9:00 am

Surgical trials & techniques
Marijan Koprivanac, MD

9:20 am

Break & Exhibits

Session 3: Heart failure with AI and AS
Moderators: Brian Griffin, MD & Christine Jellis, MD, PhD

9:45 am

Managing HF in AS with multivalve disease
Brian Griffin, MD

9:55 am

Aortic stenosis & heart failure
Amar Krishnaswamy, MD

10:05 am

Case Presentation: Cardiogenic shock presenting to CICU
Christine Jellis, MD, PhD

10:10 am

Critical care cardiology assessment & decision making
Leslie Cho, MD

10:20 am

Interventional: TAVR in cardiogenic shock
Grant Reed, MD

10:30 am

Surgical: Any role for surgery or MCS?
Marijan Koprivanac, MD

Session 4: Managing Post-interventional Issues – Rapid Fire
Moderators: Brian Griffin, MD & L. Leonardo Rodriguez, MD

10:50 am

Importance of prosthesis-patient mismatch after TAVR: Definitions, incidence & clinical relevance
L. Leonardo Rodriguez, MD

11:00 am

Planning for TAV-in-TAV: Technical considerations & long-term risks
Amar Krishnaswamy, MD

11:10 am

Optimal anti-thrombotic therapy after TAVR: Updates & controversies
Grant Reed, MD

11:20 am

Predictors of pacemaker dependency
Samir Kapadia, MD

11:30 am

Management of hemodynamic collapse during TAVR management in
Amar Krishnawamy, MD

11:40 am

Cerebral embolic protection during TAVR: what does the data support?
Samir Kapadia, MD

11:50 am

Management of paravalvular leaks after SAVR & TAVR
Grant Reed, MD

12:15 pm

Adjourn