USCAP Modern Breast Pathology Practical Updates from the International Society of Breast Pathology (ISBP) 2026

Original release date: April 8, 2026
Course Description
Join USCAP and the International Society of Breast Pathology (ISBP) for a comprehensive overview and update of the rapidly evolving field of breast pathology. The course will highlight the changes in the new WHO classification of breast tumors (6th Ed.), review the most current guidelines in biomarker testing to guide patient management, and cover diagnostic challenges of benign to malignant lesions with an emphasis on identifying histologic mimics.
Target Audience
Practicing academic and community pathologists, and pathologists-in-training
Learning Objectives
Upon completion of this educational activity, learners will be able to:

Discuss diagnostic challenges in breast pathology and how to resolve difficult cases.
Review recent updates on biomarker testing in breast cancer.
Discuss the WHO Classifications updates.

The USCAP Modern Breast Pathology – Practical Updates from the International Society of Breast Pathology (ISBP) 2026 is best for pathologists, oncologists, and trainees who want authoritative, evidence‑based updates on breast pathology with direct application to diagnostic practice. It emphasizes integrating modern molecular insights, refining histopathologic criteria, and applying international consensus standards to improve patient outcomes.
Who Should Attend

Practicing pathologists interpreting breast biopsies and resections.
Breast oncologists & surgeons collaborating with pathology for treatment planning.
Residents & fellows in pathology seeking structured training in breast pathology.
Cytopathologists working with breast cytology and fine‑needle aspiration.
Academic faculty & researchers focusing on breast cancer and related diseases.

What You’ll Learn

Histopathology essentials: benign, premalignant, and malignant breast lesions.
Updates in classification systems: WHO and ISBP consensus guidelines.
Molecular pathology: biomarkers, genetic testing, and precision medicine applications.
Challenging cases: pitfalls, mimics, and differential diagnoses in breast pathology.
Clinical correlation: how pathology informs surgical and oncologic management.
Case‑based instruction: practical examples from international experts.

 
+ Topics:

Updates from the WHO Classification of Breast Tumors, 6th Edition – Puay Hoon Tan, MD, MBBS, FRCPA, FRCPath
Classification of Special Type Carcinomas – Hannah Y. Wen, MD, PhD
Unusual Mimickers and Diagnostic Pitfalls – Ashley M. Cimino-Mathews, MD
Assessment of Breast Specimens After Neoadjuvant Therapy – Popi Siziopikou, MD, PhD
Special Type Carcinomas – Hannah Y. Wen, MD, PhD
Unusual Mimickers – Ashley M. Cimino-Mathews, MD
The Ever-Changing Field of Biomarker Testing – Hannah Y. Wen, MD, PhD
Challenging Papillary Lesions – Marina De Brot, MD, PhD
Pitfalls in Spindle Cell Lesions – Ashley M. Cimino-Mathews, MD
Small Glandular Proliferations – Benjamin C. Calhoun, MD, PhD
Challenging Papillary Lesions – Marina De Brot, MD, PhD
Small Glandular Proliferations- Benjamin C. Calhoun, MD, PhD
Updates in the Classification of Lobular Carcinoma – Benjamin C. Calhoun, MD, PhD
Targeted Use of Immunohistochemistry in Breast Pathology Diagnoses – Marina De Brot, MD, PhD
Atypical Intraductal Proliferations – Popi Siziopikou, MD, PhD
Fibroepithelial Lesions – Puay Hoon Tan, MD, MBBS, FRCPA, FRCPath
Atypical Intraductal Proliferations – Popi Siziopikou, MD, PhD
Fibroepithelial Lesions – Puay Hoon Tan, MD, MBBS, FRCPA, FRCPath
FREE SECTION: Panel Discussions