by Pascal Dolle, Karen Niederreither

The Retinoids: Biology, Biochemistry, and Disease provides an overview and synthesis of the retinoid molecules, from basic biology and mechanisms to diseases and therapy. Divided into four sections, the book covers retinoic acid signaling from biochemical, genetic, developmental, and clinical perspectives.

Chapters in section one explain vitamin A metabolism, storage, and tissue delivery mechanisms, the evolution of the retinoic acid signaling pathway, section two covers retinoic acid receptors and control of gene expression, while section three focuses on development and includes chapters on the teratology of retinoids and RA roles in embryonic development. Section four explores the physiological functions of retinoids, and section five is focused on the retinoid pathway in disease, including metabolic diseases, obesity, diabetes, leukemia, and breast cancer, as well as therapies and prevention.

Comprehensive in scope and written by leading researchers in the field, The Retinoids will be an essential reference for biologists, biochemists, geneticists and developmental biologists conducting retinoid research, as well as for clinicians and pharmacists in clinical research involving retinoids.

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