Telomeres, Diet and Human Disease: Advances and Therapeutic Opportunities (PDF)

The maintenance of telomeres―repetitive sequences at the end of chromosome―is crucial to maintaining good health. The process of telomere maintenance pathways playing a vital role in the aging process, along with diseases such as cancer, atherosclerosis, and others. As a result, telomere maintenance has become a prime target for patient therapies. This book provides insight into the advances in telomere research, specifically how it applies to human health. The book focuses on how lifestyle and dietary factors affect the telomerase maintenance process. The book delves into mechanisms such as oxidative stress and the role of sirtuins, examining how dietary patterns, such as the Mediterranean diet, can modify these mechanisms.