Natural Products and their Bioactives in Antidiabetic Drug Discovery (PDF)

By Kanti Bhooshan Pandey, Maitree Suttajit, Pinar Atukeren

Introduction: “Natural Products and Their Bioactives in Antidiabetic Drug Discovery” offers a comprehensive insight into harnessing bioactive compounds for targeting, preventing, and managing diabetes effectively. This book serves as a bridge between public research institutes and private companies, contributing to the ongoing quest for innovative drugs to combat diabetes. The text is enriched with case studies and illustrative examples, enhancing reader comprehension.

Key Features:

1. Foundations and Progress: Part one delves into fundamental concepts of diabetes mellitus (DM), recent drug discovery advancements, and explores various druggable targets and challenges associated with diabetes management.
2. Type-1 Diabetes Focus: Part two examines bioactive compounds that target Type-1 Diabetes, presenting insights into potential therapeutic strategies.
3. Type-2 Diabetes Exploration: Part three narrows down the focus to Type-2 Diabetes, shedding light on bioactive compounds that hold promise in managing this prevalent form of diabetes.
4. Gestational Diabetes Management: In part four, contributors delve into the prevention and management of gestational DM using natural compounds.

Themes Explored: The book spans a wide array of topics, including:

• Exploring the impact of obesity as a risk factor for patients with T1DM and the potential role of nutritional therapy in its management.
• Novel approaches utilizing natural non-insulin drugs to enhance therapeutic outcomes against T1DM.
• Evaluating the effectiveness of functional foods in intervening in diabetic complications, supported by realistic results from clinical trials.
• Harnessing nanotechnology to improve the bioavailability and reduce the threshold dose of bioactive compounds.
• Unraveling the mechanisms of action of various polyphenols with antidiabetic properties, along with the immunomodulatory roles of NPs bioactives in T1DM therapy.
• Investigating the influence of natural products on the genetics of gestational diabetes.

Conclusion: “Natural Products and Their Bioactives in Antidiabetic Drug Discovery” stands as an indispensable resource for professionals and researchers engaged in drug discovery and development, healthcare, medicinal chemistry, phytochemistry, plant science, and toxicology. With its thorough coverage of recent research on leveraging bioactives from natural products to address diabetic complications, this book contributes to advancing our understanding of diabetes management strategies and potential therapeutic breakthroughs.

Product Details

• Publisher ‏ : ‎ Wiley; 1st edition (August 1, 2023)
• Language ‏ : ‎ English
• eBook Digital ‏ : ‎ 352 pages
• ISBN-10 ‏ : ‎ 1119983312
• ISBN-13 ‏ : ‎ 978-1119983316