Medicinal Chemistry, 2nd Edition (PDF)

by Norma K Dunlap, Donna M Huryn

This book provides a concise introduction to the medicinal chemistry of therapeutically active compounds. Written in an accessible style, it offers a brief overview of the drug development process, from discovery to approved drug. Emphasizing medicinal chemistry strategies, the content is organized by target as well as therapeutic area drug classes. It covers existing drugs and the discovery process that led to their development. Aimed at students and professionals interested in drug discovery, Medicinal Chemistry requires little prior knowledge, making it ideal for classroom and training seminar use.

Written by experts in the field, this outstanding new edition explains medicinal chemistry on chemical mechanism terms, allowing for a more interesting and user-friendly text.

Includes valuable insights toward the various pathways taken by the pharmaceutical industry in drug discoveries.

Enhanced text includes questions raised and suggestions made from students in the authors’ medicinal chemistry class.

Content provided to enhance the text includes a solutions manual, PowerPoint slides for lecture outlines, and especially for the earlier chapters, a selection of videos. An accompanying website will be updated to include additional material: (1) Journal Club exercises―current journal articles with guiding questions for student analysis (two per chapter); (2) additional case studies; (3) organic synthesis analysis―selected syntheses, both discovery and process, will be discussed; and (4) updates on current advances in the field of medicinal chemistry.

The book benefits a diverse audience, including upper-level undergraduates and graduates who are studying in the fields of medicinal chemistry and drug discovery, as well as scientists working in the pharmaceutical industry.