Innovative Therapeutic Approaches by Crispr/Cas9 in Cancer Therapy (PDF)

by Kiavash Hushmandi, Alan Prem Kumar

This book explores the groundbreaking potential of CRISPR/Cas9 gene-editing technology in revolutionizing cancer treatment. This collection of chapters delves into the application of CRISPR/Cas9 across a variety of cancers, including lung, breast, brain, gastric, pancreatic, colorectal, liver, prostate, bladder, cervical, ovarian, and bone cancers. Each chapter provides an in-depth analysis of how CRISPR/Cas9 can target and modify cancerous cells at the genetic level, offering the potential for highly personalized and precise therapies. The book also addresses the growing challenge of cancer drug resistance, detailing how CRISPR/Cas9 is being employed to study, understand, and potentially reverse resistance mechanisms, offering new hope for patients who have exhausted conventional treatment options. Furthermore, the integration of nanoparticles for efficient delivery of the CRISPR/Cas9 system is highlighted, providing a promising avenue for overcoming delivery challenges in cancer therapy.