Cleveland Clinic International Perspectives on Liver Failure in Critical Care 2025

Based on the program details for the Cleveland Clinic International Perspectives on Liver Failure in Critical Care 2025, here is the overview of this specialized virtual symposium.
The International Perspectives on Liver Failure in Critical Care 2025 was a targeted, one-day virtual symposium designed to address the complex challenges of managing critically ill patients with liver disease. Hosted by the Cleveland Clinic’s renowned Medical Intensive Liver Unit (MILU), the course focused on the intersection of Hepatology and Critical Care Medicine.
It emphasized a multidisciplinary approach to life-threatening conditions such as Acute Liver Failure (ALF) and Acute-on-Chronic Liver Failure (ACLF), bridging the gap between medical management and liver transplantation.
+ What You Will Learn
The curriculum was highly specific to the ICU setting, providing actionable strategies for:

Hemodynamic Stabilization: Managing the unique vasodilation and shock states seen in liver failure (cirrhotic cardiomyopathy).

Neuromonitoring: “When and How” to monitor for cerebral edema and intracranial hypertension in high-grade hepatic encephalopathy.

Renal-Hepatic Crosstalk: Updates on Hepatorenal Syndrome (HRS-AKI) and the timing of renal replacement therapy (CRRT) as a bridge to transplant.

Transplant Candidacy: Determining when a patient is “too sick for transplant” versus when high-risk transplantation is the only viable option.

Multidisciplinary Protocol: How to coordinate care between intensivists, hepatologists, and transplant surgeons to optimize waitlist mortality prioritization.

+ Event Details

Event: International Perspectives on Liver Failure in Critical Care 2025

Date: Tuesday, October 7, 2025

Format: Live Stream / Virtual Symposium

Director: Aanchal Kapoor, MD, MEd (Director of the Cleveland Clinic Medical Intensive Liver Unit).

+ Who Should Attend
This course was designed for the critical care team managing decompensated liver disease:

Intensivists (Critical Care Physicians): Who manage non-transplant and pre-transplant liver patients in the ICU.

Hepatologists & Gastroenterologists: Seeking updates on critical care aspects of their patients.

Anesthesiologists: Specifically those involved in liver transplantation.

Advanced Practice Providers (NPs/PAs): Working in MICU or Liver Transplant units.

+ Why Attend

Niche Expertise: Few conferences focus exclusively on the critical care aspect of liver failure; most are broader hepatology meetings. This filled a vital knowledge gap.

MILU Experience: The Cleveland Clinic MILU is one of the few dedicated liver ICUs in the world. Attendees gained insights into their specific protocols for managing high-MELD patients.

Complex Decision Making: The course directly addressed the “gray areas” of medicine—such as ethical considerations in transplant listing for patients with multiple organ failure.

 
+ Topics:
Tuesday, October 7, 2025

12:05 pm Evolution of Liver Critical Care- Lessons Learned Georg Auzinger, Dr Med Univ, FRCP, AFICM, EDIC
12:30 pm Management of ALF- Multidisciplinary Approach Constantine (Dean) Karvellas, MD, SM, FRCPC, FCCM
12:55 pm Neuromonitoring – When and How Catherine Hassett, DO
1:20 pm Hemodynamic Alterations and Management Strategies Aanchal Kapoor, MD, MEd
1:45 pm Panel Discussion and Q&A Moderators: Aanchal Kapoor, MD, MEd and Eduardo Mireles-Cabodevila, MD Faculty: Georg Auzinger, Dr Med Univ, FRCP, AFICM, EDIC, Constantine (Dean) Karvellas, MD, SM, FRCPC, FCCM, and Catherine Hassett, DO
2:00 pm Break
2:15 pm Peri-op Cardiac Risk Assessment and Approach to Transplant in ALF and ACLF Maan Fares, MD
2:40 pm Acute Kidney Injury/Hepatorenal Syndrome and Bridge to Transplantation Andrew Allegretti, MD, MSc
3:05 pm ACLF and Transplant Waitlist Mortality Prioritization Jody C. Olson, MD, FACP, FCCM
3:30 pm When it is Too Sick for Transplant Christina Lindenmeyer, MD
3:55 pm Peri-op Hemodynamic Management Matt Siuba, DO
4:20 pm Panel Discussion and Q&A Moderators: Jacek B. Cywinski, MD, FASA, Siddharth Dugar, MD, and Koji Hashimoto, MD, PhD Faculty: Maan Fares, MD, Andrew Allegretti, MD, MSc, Jody C. Olson, MD, FACP, FCCM, Christina Lindenmeyer, MD, and Matt Siuba, DO
4:35 pm Wrap Up Aanchal Kapoor, MD, MEd, Christina Lindenmeyer, MD, and Eduardo Mireles-Cabodevila, MD
4:40 pm Adjourn