USCAP Updates of the WHO Classification of Brain and Pituitary Tumors 2024

Original release date: June 20, 2024
Course Description
Capitalizing on the advancement in the molecular diagnostics, the 2021 WHO classification of central nervous system (CNS) tumors recommended substantial changes in taxonomy, nomenclature and grading of CNS tumors. Furthermore, 22 new tumor types/subtypes were introduced and 13 revised terminologies for tumor types/subtypes were implemented. This case-based course will provide a framework for using the contemporary molecular and morphological diagnostic criteria in pediatric and adult brain tumors and pituitary gland neoplasms. Expert faculty will lead sessions to ensure pathologists become familiar with these major changes in diagnostic criteria and utilize them in their daily practice.
This course is a collaboration between the American Association of Neuropathologists and USCAP.
Target Audience
Practicing academic and community pathologists, and pathologists-in-training
Learning Objectives
Upon completion of this educational activity, learners will be able to:

Apply the 2021 CNS WHO taxonomy, nomenclature, grading and classification of adult-type diffuse gliomas.
Integrate morphologic and molecular diagnostic techniques to diagnose pediatric-type diffuse low-/high-grade gliomas.
Explain the role of integrated molecular diagnosis and histological criteria in the classification of other CNS tumors including ependymal, dural-based, nerve sheath, and CNS embryonal tumors.
Summarize the newly described tumor type/subtypes in the 2021 CNS WHO.
Apply the 2022 WHO classification of pituitary neuroendocrine tumors (PitNETs) according to cell-lineage and cell type.
Discuss the non-neuroendocrine tumors of the sellar region.
List the most common nervous system tumors and associated clinical scenarios that should raise suspicion for genetic tumor syndromes.

 
+ Topics:

Sellar Region Tumors 1 (Neuroendocrine) – Sylvia L. Asa, MD, PhD Section: 1 Presentation 2 Documents
Diffuse Gliomas – Arie Perry, MD Section: 1 Presentation 2 Documents
Sellar Region Tumors 2 (Non-Neuroendocrine) – Sylvia L. Asa, MD, PhD Section: 1 Presentation 2 Documents
Meningiomas and Mesenchymal Tumors – Arie Perry, MD Section: 1 Presentation 2 Documents
Ependymal and CNS Embryonal Neoplasms – Daniel Brat, MD, PhD Section: 1 Presentation 2 Documents
Nerve Sheath and Melanocytic Tumors – Melike Pekmezci, MD Section: 1 Presentation 2 Documents
Circumscribed Glial and Glioneuronal Tumors – Daniel Brat, MD, PhD Section: 1 Presentation 2 Documents
Genetic Tumor Syndromes of the Nervous System – Melike Pekmezci, MD Section: 1 Presentation 2 Documents