UChicago Medicine Fredric L. Coe Symposium on Kidney Stone Disease and Mineral Metabolism 2025

1. Overview
The UChicago Medicine Fredric L. Coe Symposium on Kidney Stone Disease and Mineral Metabolism 2025 provides an in-depth clinical review of kidney stone pathophysiology, prevention, and management. The program explores mineral metabolism, idiopathic hypercalciuria, kidney stone compositional analysis, and the impact of acid balance on overall stone risk.
Course Date: October 9, 2025

This activity brings together national leaders in the field to explore recent advancements in the understanding of renal physiology, pathophysiology, and mechanisms underlying kidney stone formation. It addresses key knowledge gaps, such as those related to hypercalciuria and acid-base disorders, by fostering discussion on current research findings and treatment approaches. Participants will gain up-to-date insights into kidney stone disease and its clinical implications.

2. Learning Objectives

Evaluate the relationship between bone health, mineral metabolism, and the development of kidney stones.

Utilize comprehensive kidney stone compositional analysis to guide targeted treatment and prevention strategies.

Analyze the pathophysiological connection between idiopathic hypercalciuria and papillary mineral deposits.

Assess the impact of systemic acid-base balance and urine acidity on clinical kidney stone risk.

Implement evidence-based approaches to diagnose, manage, and prevent brushite stones in clinical practice.

3. Target Audience

Best for nephrologists and urologists who want specialized updates on kidney stone disease, mineral metabolism, and compositional analysis.

4. Topics

01 2025 Symposium Welcome

02 Opening Remarks

03 Chairman’s Remarks

04 Bones and Stones – Almost a Decade with Fred and Where it Led

05 Kidney Stone Compositional Analysis – The Other Half of the Pliers

06 Idiopathic Hypercalciuria and Papillary Mineral Deposits – What is the Connection

07 Acid and Stone Risk

08 The Brushite Story

09 The Stone Clinic as a Living Laboratory – A Legacy of Education Based in Clinical Care

10 2025 Symposium Concluding Remarks