By Buddhi Prakash Jain, Shyamal K. Goswami, Tapan Sharma
Post-transcriptional Gene Regulation in Human Disease, a new volume in the Translational Epigenetics book series, offers a thorough overview and discussion of post-transcriptional genetic control mechanisms and their roles across various pathologies and human developmental outcomes, along with regulatory mechanisms targeted for therapeutic approaches. The book is broadly divided in two parts: early chapters describe the basics of post-transcriptional gene regulation, associated epigenetic mechanisms, the role of RNA binding proteins, the evolution of post-transcriptional gene regulation, and methods to study these mechanisms. The second half of the book includes deeper discussion of post-transcriptional gene regulation across specific diseases and therapeutics targets. Various post-transcriptional events, including alternative splicing and polyadenylation, mRNA stability, and miRNAs and their involvement in the disease progression, are examined in detail.

Product Details

• Publisher ‏ : ‎ Academic Press; 1st edition (August 30, 2022)
• Language ‏ : ‎ English
• Digital eBook ‏ : ‎ 394 pages
• ISBN-10 ‏ : ‎ 0323913059
• ISBN-13 ‏ : ‎ 978-0323913058
• ISBN-13 ‏ : ‎ 9780323913058
• eText ISBN: 9780323914246