Methods in Cancer Stem Cell Biology (EPUB)

Product Details

• Publisher ‏ : ‎ Springer; 1st ed. 2023 edition (May 27, 2023)
• Language ‏ : ‎ English
• eBook Digital ‏ : ‎ 260 pages
• ISBN-10 ‏ : ‎ 9819913306
• ISBN-13 ‏ : ‎ 978-9819913305

This book describes the use of stem cells and cancer stem cell generation in the inflammatory microenvironment (cancer-inducing niche) using induced pluripotent stem cells. The 20 chapters of this book cover topics such as generating pluripotent stem cells, converting normal stem cells to cancer stem cells, enriching, isolating and evaluating cancer stem cells. Methods for evaluating the characteristics of cancer stem cells and possible therapies against them are also discussed.

By Said M. Afify, Masaharu Seno, this comprehensive guide features the research of the authors’ group, which was the first to generate cancer stem cells from stem cells in the presence of inflammatory conditions. The development of induced pluripotent stem cells has provided a new approach to studying cancer initiation by producing cancer stem cells without introducing mutations or foreign genes.

This book provides easy-to-follow protocols that help researchers in the study of cancer stem cells. Illustrations help readers understand how the method of cancer stem cell generation can be applied as an essential method for assessing the carcinogenic potential of various non-mutagenic compounds. It will be a useful resource for graduate students, researchers, technicians, and physicians working in academic, hospital, and pharmaceutical settings.