In this twelfth book of the Medical Masterclass series, Rheumatology and clinical immunology, we cover all the common clinical presentations. Topics include taking a patient history; physical signs that patients may have; planning a strategy for investigation and treatment; and discussing difficult issues with patients and their relatives (useful for both clinical practice and PACES exam practise). The key points are emphasised, and this book also includes self-assessment questions (SAQs) in the style of the MRCP(UK) Part 1 and Part 2 exams. This third edition of Medical Masterclass is updated to reflect changes to the MRCP(UK) exam. The Medical Masterclass books have an easy-to-read format, clinical images and highlighted key points throughout. Considered to be the most comprehensive MRCP(UK) revision package available. Produced by the Royal College of Physicians, the Medical Masterclass series is written by over 75 authors and contributors, under the editor- in-chief Dr John Firth DM FRCP.