This book focuses on Intraoperative Imaging in Neurosurgery. Neurosurgery is a branch of medicine that focuses on the prevention, diagnosis and treatment of the central nervous system (brain and spinal cord) and the peripheral nervous system. This book consists of 18 chapters, which include history of neuroimaging, intraoperative imaging in neurosurgery, intraoperative magnetic resonance imaging, low-field intraoperative magnetic resonance imaging, two room versus single room intraoperative magnetic resonance imaging setup, anesthesia for intraoperative magnetic resonance imaging, intraoperative computed tomography, CT-based navigation in brain and spine surgery, intraoperative ultrasound, ALA dye in high-grade gliomas, intraoperative imaging in epilepsy surgery, impact of intraoperative magnetic resonance imaging on extent of resection, intraoperative imaging in pituitary surgeries, intraoperative imaging in skull base surgeries, role of intraoperative imaging in cerebrovascular surgeries, multimodality image-guided neurosurgery, and future of navigation and intraoperative imaging. Strong motivation to compile the book was to spread awareness and education regarding the available technology today that can help in making neurosurgery more safe and precise.