International Review of Neurobiology, Volume 158 in this ongoing series, highlights new advances in the field, with this release including sections on Brain Networking, Computational Models, Adaptive DBS, Invasive cortical stim, Non-invasive CS – TMS, Non-invasive CS – tDCS, New development SCS, Brain machine interface, Optogenetics and Neuromdul, DTI, Multimodal imaging, Neuromodulation in psychiatry, Neuromodulation in Alzheimer’s, Focused Ultrasound Neuromodulation, and From Talk to Action – Canadian Leadership Ethics and Neurotechnology.