Cleveland Clinic Advanced Endoscopy Course 2025

The Cleveland Clinic Advanced Endoscopy Course (CADEC) 2025 is the 4th annual edition of this high-intensity international symposium. It continues its tradition of bridging the gap between medical gastroenterology and surgical intervention, with a specific focus on “Organ Sparing” and “Incisionless” techniques.
For 2025, the course places a renewed emphasis on Metabolic Endoscopy (integrating GLP-1 agonists with endoscopic procedures) and Third Space Endoscopy (POEM, ESD). It is distinguished by its extensive Hands-On Surgical Skills Lab, which utilizes ex-vivo models to allow attendees to practice complex maneuvers under the guidance of world-renowned faculty.
+ What You Will Learn
The curriculum is designed to move attendees from “theory” to “technical application.” Key learning objectives include:

Bariatric Synergy: How to combine anti-obesity medications (GLP-1s) with procedures like Endoscopic Sleeve Gastroplasty (ESG) and Transoral Outlet Reduction (TORe) for comprehensive weight management.

Submucosal Dissection: Mastering the technical variances between Esophageal ESD (Western approach) and Gastric ESD (Eastern approach), including traction strategies to increase speed and safety.

Complication Management: “Bailing out” of difficult situations—managing perforations, leaks, and fistulas using advanced suturing and vacuum therapy (EVT).

Interventional EUS: Techniques for placing Lumen-Apposing Metal Stents (LAMS) for gallbladder drainage and pancreatic fluid collections.

+ Event Details

Event: Cleveland Clinic Advanced Endoscopy Course (CADEC) 2025

Dates: September 26–27, 2025 (Friday–Saturday)

Location: InterContinental Cleveland Hotel & CCF Simulation Skills Center, Cleveland, Ohio, USA.

Course Director: Roberto Simons-Linares, MD.

+ Who Should Attend

Advanced Endoscopists: Seeking to refine their skills in ESD and third-space endoscopy.

Bariatric Surgeons: Interested in adding flexible endoscopic options (like ESG or revision procedures) to their practice.

General Gastroenterologists: Who want to understand the new indications for referring patients for advanced procedures (e.g., when to refer for POEM vs. Heller Myotomy).

Endoscopy Nurses & Techs: Who support these complex cases and need to understand device setup and accessory exchange.

+ Why Attend

Hands-On Volume: Unlike many courses that offer only brief simulation exposure, CADEC features massive 4-hour lab blocks covering everything from Z-POEM (for Zenker’s) to Transoral Incisionless Fundoplication (TIF).

Multi-Disciplinary Faculty: The faculty includes both GI and Surgical experts (e.g., Dr. Amit Bhatt, Dr. John Vargo), providing a balanced perspective on the “Medical vs. Surgical” management of diseases like obesity and Achalasia.

Innovation: The 2025 agenda includes specific sessions on “Endorobotics,” exploring whether robotic platforms will replace current manual endoscopic techniques.

+ Topics

01 Endoscopic Closure Methods for Esophageal Perforation
02 Engineering Access – Addressing Biliary Obstruction in a Complex Surgical Reconstruction
03 Obesity and GERD – What Are the Options
04 Updates in Barrett’s Esophagus
05 Endoscopic Management of a Complex Rectal Perforation
06 What’s New in Interventional EUS
07 Third Space Update – POEM