Neurotoxicity of Aluminum, 2nd Edition (PDF)

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This book explores the link between aluminum neurotoxicity and cognitive impairment/Alzheimer’s disease. It discusses aluminum levels in the brain, its relation to pathological features of AD, its mechanism in oxidative stress and cell death, and its role in synaptic plasticity and electrophysiological variation. The second edition updates eight chapters and includes new content on aluminum-induced AD-like features and neurotoxic effects of aluminum and aluminum alloy nanoparticles. Publisher: Springer Nature Singapore; August 3, 2023. ISBNs: 9789819915910 and 9789819915927.

Category: Springer Ebook

Description

Neurotoxicity of Aluminum, 2nd Edition (PDF Book)

by Qiao Niu (Author)

Introduction: The second edition of “Neurotoxicity of Aluminum” dives into the intricate relationship between aluminum exposure and cognitive impairment, particularly in the context of Alzheimer’s disease (AD). Author Qiao Niu presents a thorough analysis of existing scientific literature alongside their own research findings, elucidating the connections between aluminum neurotoxicity, neurofibrillary tangles, amyloid beta accumulation—hallmarks of AD—and cognitive decline. With a focus on aluminum’s distribution within the brain, its role in oxidative stress and cell death, and its influence on electrophysiology and synaptic plasticity, this edition delves into the multifaceted aspects of aluminum’s impact on neurological health.

Key Features:

Comprehensive Exploration: The book provides an all-encompassing review of aluminum neurotoxicity, exploring the intricate ties between aluminum exposure and cognitive impairment, particularly Alzheimer’s disease.
Pathological Insights: Through scientific literature and original research, the book reveals aluminum’s connection to neurofibrillary tangles and amyloid beta, key pathological features of AD. It delves into aluminum’s role in initiating these features and the ensuing cognitive decline.
Complex Speciation Chemistry: The book underscores the importance of understanding aluminum’s complex speciation chemistry in relation to biological systems, illuminating its role in oxidative stress, cell death pathways, and synaptic impairment.
Emerging Topics: This second edition introduces new content covering aluminum-induced AD-like pathological features, the neurotoxic effects of aluminum nanoparticles and alumina nanoparticles, and their neurodevelopmental consequences.
Updated Insights: Eight chapters are updated to include the latest research findings, ensuring that readers have access to the most recent information in the field.

Target Audience: “Neurotoxicity of Aluminum, 2nd Edition” is intended for researchers, scientists, clinicians, and students seeking a comprehensive understanding of the complex relationship between aluminum exposure and cognitive impairment, with a focus on Alzheimer’s disease. Its comprehensive coverage makes it an essential reference for individuals across the spectrum of expertise.

Conclusion: “Neurotoxicity of Aluminum: Unveiling Cognitive Impairment and Alzheimer’s Disease Links, 2nd Edition” offers a deep exploration of the intricate links between aluminum exposure and cognitive decline, particularly in the context of AD. Author Qiao Niu’s integration of scientific literature, original research, and updated insights results in a comprehensive resource that delves into the multifaceted aspects of aluminum neurotoxicity. This edition serves as a valuable reference for researchers, clinicians, and students aiming to comprehend the complex mechanisms underlying aluminum’s impact on neurological health. By providing readers with up-to-date information and in-depth insights, this book contributes significantly to our understanding of the role of aluminum in cognitive impairment and its potential implications for Alzheimer’s disease.