The Clinical Manual of Cultural Psychiatry was developed over more than 18 years, first as a course, then as a successful and highly regarded manual for use by mental health practitioners in evaluating patients who identify themselves as belonging to a cultural or minority group. The second edition represents the further evolution of the field and is needed now more than ever in our increasingly diverse world. The book has been not only thoroughly updated but also expanded to embrace additional dimensions and segments of society. Mental health issues experienced more frequently by women and the cultural factors affecting the mental health of lesbian, gay, bisexual, and transgender individuals, as well as religious and spiritual issues, are explored in four new chapters that round out coverage of the nation’s four major ethnic minority groups. The new edition is also updated with the DSM-5[registered] Outline for Cultural Formulation and the new Cultural Formulation Interview and comes with access to online video examples using simulated patients to illustrate how to use these tools. Focused on promoting both understanding and developing cultural competency for clinicians, the new second edition of the Clinical Manual of Cultural Psychiatry represents a major advancement in this critically needed area.