Anticancer Therapeutics: From Drug Discovery to Clinical Applications (PDF)

An overview and in-depth analysis of anticancer drugs

This one-of-a-kind text targets both undergraduate and postgraduate readers by providing them with a comprehensive understanding of all aspects of the science of anticancer drugs. It combines the chemistry, pharmacology, and clinical applications of these drugs into one fully integrated source.

Cancer is the second leading cause of death worldwide, and the ever-changing tumor environment creates an increasing need for safer and more effective anticancer drugs. The $100 billion cancer drug market is growing year after year as our understanding of cancer continues to grow and lead to the development of new drugs for clinical use.

Anticancer Therapeutics is organized into three sections. The first section is an introduction to cancer and therapeutics, covering the etiology and cellular and molecular basis of cancer. In the second section, the authors focus on anticancer agents – their discovery, synthesis, mode of action, mechanisms of resistance, and adverse reactions. The third section concentrates on specific cancers, explaining how the drugs discussed in section two are used, both individually and in combination, to treat different cancers.

• Integrates basic science, including chemistry and pharmacology, with clinical medicine in the context of cancer therapeutics

• Authored by specialists in medicinal chemistry, pharmacology, and oncology
• Includes full-color images throughout, illustrating how drugs bind to cellular targets and exert their pharmacological effect
• Divided into three sections, covering the etiology and cellular and molecular basis of cancer, anticancer agents, and drug applications for different cancers.

This textbook is suitable for undergraduates studying medicine, nursing, medicinal chemistry, pharmacy, pharmacology, and other allied health/life sciences. It also serves as a valuable bench reference for those working in academia and industry within the field, including pharmacists, medics, and pharmaceutical researchers.