Alpha-1 antitrypsin deficiency and replacement therapy – Current developments and clinical significance (UNI-MED Science) (PDF)
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File Size : 1.6 MB
This textbook provides an overview of Alpha-1 antitrypsin deficiency (AATD) with causes and genetics, diagnosis and therapy, the role of comorbidities, and other topics. It is a practice-oriented volume that will be helpful in the care of patients with AATD. Published by UNI-MED Verlag AG in June 2021 and written by Andreas Rembert Koczulla. ASIN: B09FRY3C3X.
Alpha-1 antitrypsin deficiency and replacement therapy – Current developments and clinical significance (UNI-MED Science) (PDF Book)
By Andreas Rembert Koczulla
Alpha-1 antitrypsin deficiency (AATD) is one of the most common genetic defects in Europe. As a consequence of the lowered A1AT serum level, the protease-antiprotease balance is disturbed, which among others can lead to an early development of emphysema. The underdiagnosis of AATD is another problematic aspect because it is suspected that only about 5 to 15% of all homozygous patients are currently identified. Usually there is also a diagnostic delay, which can be 5 years or more.This textbook provides an overview of AATD with causes and genetics, diagnosis and therapy, the role of comorbidities and further topics such as vaccinations, sport and physical activities as well as the very complex aspects of a lung transplant. The increasing importance of imaging is addressed as well as the overall clinical evaluation and the need for follow-up examinations. The result is a very practice-oriented volume that will be very helpful in everyday clinical practice in the care of patients with AATD.
Product Details
- ASIN : B09FRY3C3X
- Publisher : UNI-MED Verlag AG; 1st edition (June 1, 2021)
- Publication date : June 1, 2021
- Language : English
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