•The book is most Authoritative and updated resource for trainees, experienced radiologists and imaging technologists.•It presents key facts in the form of tables and boxes. •Covers most recent issues and other important problems not included in the last edition such as Genomics, Radiogenomics, Texture analysis, Safety of Gadolinium(GD)-based contrast, Pediatric Interstitial lung disease(ILD), Pediatric Budd-Chiari syndrome, and pediatric head & neck Imaging.•It not only provides an update on all main imaging modalities, viz. CT, MRI, Ultrasound and Digital Radiography, but also the trending topics.•Four new chapters and several new images have been added to make it richly illustrative.