By Chandra S. Boosani, Ritobrata Goswami
Epigenetics in Organ Specific Disorders, a new volume in the Translational Epigenetics series, provides a foundational overview and nuanced analysis of epigenetic gene regulation distinct to each organ type and organ specific disorders, fully elucidating the epigenetics pathways that promote and regulate disease. After a brief introduction, chapter authors compare epigenetic regulations across normal and disease conditions in different organ tissues, exploring similarities and contrasts. The role of epigenetic mechanisms in stem cells, cell-matrix interactions and cell proliferation, cell migration, cellular apoptosis, necrosis, pyknosis, tumor suppression, and immune responses across different organ types are examined in-depth.Organ specific epigenetic mechanisms and biomarkers of early use in developing drugs, which can selectively target the organ of interest, are also explored to enable new precision therapies.

Product Details

• Publisher ‏ : ‎ Academic Press; 1st edition (December 19, 2022)
• Language ‏ : ‎ English
• Digital eBook ‏ : ‎ 666 pages
• ISBN-10 ‏ : ‎ 012823931X
• ISBN-13 ‏ : ‎ 978-0128239315