Harvard 49th Annual Intensive Review of Internal Medicine 2026

With an extensive array of lectures, case discussions, and board preparation sessions, this program is the most comprehensive review of Internal Medicine offered by the clinical faculty of Harvard Medical School. The program offers accelerated learning both for clinicians seeking a practical and comprehensive Internal Medicine review and for physicians preparing to take the ABIM board examination.

The Acclaimed Clinical Update and Board Review
The 49th annual Intensive Review of Internal Medicine will be held July 19–26, 2026. You have the option to attend either live online or in person in Boston, MA. All sessions will be recorded and made available to all participants to view online, at your convenience, for 60 days following the course.
With an extensive array of lectures, case discussions, and board preparation sessions, this program is the most comprehensive review of internal medicine offered by the clinical faculty of Harvard Medical School. It offers accelerated learning:
>> For clinicians seeking a practical and comprehensive review that ensures you are up to date across all major fields of internal medicine:

New options for diagnosis: what to choose, when, and why
Treatment and care management strategies to optimize patient outcomes
How to avoid medical mistakes
Improved approaches to common and complex clinical challenges
Navigating screening controversies
Additional details

>> For physicians preparing to certify or recertify and seeking a rigorous, proven preparatory course in advance of taking the ABIM board examination:

Board review questions
Sessions to guide efficient preparation and study
Four practice exam sessions
Study guides
Test-taking strategies and skills development
Additional details

>> New in 2026: Four workshops dedicated to advancing your understanding and clinical use of artificial intelligence:

AI for Clinician Experience and Beyond
Escaping the AI Rut: Reimagining Learning, Purpose, and Power in Medicine
The Die Is Cast: Two Competing Views of the Future of Physician-AI Collaboration and the Future of the Clinical Mind
AI Is Not Coming for Your Job: An Insider Industry Perspective

OUTCOMES-DRIVEN EDUCATION
This past year has introduced an avalanche of critically important updates and medical advances that need to be understood and deployed for state-of-the-art patient care. Intensive Review of Internal Medicine (IRIM) synthesizes this vast amount of information and presents it with efficiency and effectiveness to ensure that you are current with these updates and the best ways to incorporate them into practice in today’s health care environment.
Sessions and board preparation span all major fields of internal medicine and are led by Harvard Medical School’s most distinguished clinical faculty in the fields of:

Cardiovascular Medicine
Oncology
Neurology
Critical Care
Nephrology
Hematology
Gastroenterology
Infectious Diseases
Pulmonary Medicine
Women’s Health
Rheumatology
Endocrinology
Allergy and Immunology
Hospital Medicine
Dermatology
Biostatistics
General Internal Medicine

Who Should Participate

» PHYSICIANS, NPs, PAs seeking a comprehensive update of the state of the art in Internal Medicine
» PHYSICIANS preparing to certify or recertify

+ Topics:

001 – Acute Kidney Injury

002 – Revisiting Electrolytes

003 – Chronic Kidney Disease

004 – Acid-Base Basics

005 – Nephrology Q&A

006 – Proteinuria, Hematuria, and Glomerular Disease

007 – Dialysis and Transplantation

008 – Hot Topic in Nephrology – Imagine Stopping Progression of Kidney Disease in Type 2 Diabetes

009 – Nephrology Q&A

010 – Nephrology Board Review

011 – Challenging Case Discussion

012 – Hypertension Cases

013 – Electrolyte and Acid-Base- Challenging Q&A – Part 1

014 – Electrolyte and Acid-Base- Challenging Q&A – Part 2

015 – Nephrology- Additional Clinical Pearls & Take-Home Messages

016 – Anemia

017 – Hypercoagulable States and New Anticoagulants

018 – Hematology Q&A

019 – Hematology Cases – Common, Complex, Rare

020 – Bleeding Disorders

021 – Hot Topic in Hematology – Gene therapy in Hemoglobinopathies and Hemophilia

022 – Hematology Q&A

023 – Board Review in Hematology

024 – Leukocytosis and Leukopenia

025 – Hematology- Additional Clinical Pearls and Take-Home Messages

026 – Chronic Liver Disease and Its Complications

027 – Esophageal Disorders

028 – Acute and Chronic Diarrhea

029 – Gastroenterology Q&A

030 – Acute and Chronic Pancreatitis

031 – Hot Topic in Gastroenterology – New Treatments for Upper Gastrointestinal Bleeding

032 – Gastroenterology Board Review

033 – A Challenging Case in Rheumatology

034 – Peptic Ulcer Disease

035 – Inflammatory Bowel Disease

036 – Hepatitis B and C

037 – Challenging Gastroenterology Cases

038 – GI- Additional Clinical Pearls and Take-Home Messages

039 – Hot Topics in Radiation Oncology – Novel Technologies in Precision Oncology – Stereotactic Body Radiation Therapy

040 – Prostate, Testicular, and Bladder Cancer

041 – Breast Cancer

042 – Oncology Q&A

043 – Lung Cancer

044 – Leukemia and Myelodysplastic Syndrome

045 – Oncology – Clinical Pearls

046 – Oncology Q&A

047 – Board Review in Oncology

048 – Multiple Myeloma

049 – Lymphoma

050 – Gastrointestinal Cancers

051 – Oncology- Take-Home Messages

052 – AI for Clinician Experience and Beyond

053 – Challenges in Venous Thromboembolism Management

054 – Heart Failure (Including HFpEF)

055 – Prevention of Cardiovascular Disease

056 – Cardiovascular Medicine Q&A

057 – Atrial Fibrillation and Common Supraventricular Tachycardias

058 – Inflammation in CardiovascularDisease – Update for 2026

059 – Adult Congenital Heart Disease

060 – Cardiovascular Medicine Q&A

061 – Board Review in Cardiology

062 – Challenging Case Discussion – Challenging Patients in Infectious Disease – A Diagnostic Toolkit for Internal Medicine

063 – Acute Coronary Syndromes

064 – Update in Valvular Disease

065 – Peripheral Artery Disease (Including Carotid and Aortic Disease)

066 – Cardiovascular Medicine Q&A

067 – Bradycardias, Syncope, and Sudden Death

068 – Hot Topic in Cardiology – Evolving Strategies for Diagnosis and Management of Cardiac Amyloidosis

069 – Pericardial Disease- Key Concepts

070 – Must-Not-Miss ECG Diagnoses Pt.1

071 – Must-Not-Miss ECG Diagnoses Pt.2

072 – Cardiomyopathies (including HCM, Amyloidosis)

073 – Cardiology – Take-Home Messages and Clinical Pearls

074 – Escaping the AI Rut – Reimagining Learning, Purpose, and Power in Medicine

075 – Diagnosis and Management of Infective Endocarditis

076 – Infection in the Immunocompromised Host

077 – Adult Immunization

078 – Infectious Disease Q&A

079 – Pneumonia in Hospitalized Patients

080 – Sexually Transmitted Diseases

081 – Hot Topic in Infectious Diseases – The Next Pandemic – Are We Prepared..

082 – Infectious Disease Q&A

083 – Infectious Disease Board Review

085 – Challenging Case Discussion Altered Mental Status in ESKD

086 – Challenging Infectious Disease Cases

087 – Tropical Medicine and Parasitology

088 – HIV Disease – An Overview

089 – Urinary Tract Infections

090 – Tuberculosis for the Non-ID Specialist

091 – Infectious Diseases- Additional Clinical Pearls and Take-Home Messages

092 – Contraception – An Update

093 – Medical Complications of Pregnancy

094 – Evaluation of the Patient with Menstrual Irregularities

095 – Women’s Health Q&A

096 – Clinical Updates and Practical Considerations in Menopause Care

097 – Osteoporosis and Metabolic Bone Disease

098 – Hot Topic in Women’s Health – New Options and Guidelines for Screening for and Preventing HPV and Cervical CA

099 – Women’s Health Q&A

100 – Women’s Health Board Review

101 – Medication Abortion and the Internist

102 – A Trauma-Informed Approach to Intimate Partner Violence

103 – Women’s Health – Take-Home Messages and Clinical Pearls

104 – The Die Is Cast – Two Competing Views ofthe Future of Physician-AI Collaborationand the Future of the Clinical Mind

105 – Pulmonary Hypertension (For the General Internist)

106 – Chronic Obstructive Pulmonary Disease

107 – Pulmonary Overview

108 – Pulmonary Medicine Q&A

109 – Asthma

110 – Pleural Effusions – A Case-Based Review

111 – Interstitial Lung Disease

112 – Hot Topic in Pulmonary Medicine – Gene and Stem Cell Therapy in Pulmonary Medicine

113 – Pulmonary Medicine Q&A

114 – Pulmonary Board Review

115 – Challenging Case Discussion

116 – Pulmonary Function Testing

117 – Sleep Apnea

118 – Chest X-Ray Interpretation for the Boards

119 – Granulomatous Lung Disease

120 – Evaluation of Unexplained Dyspnea

121 – Assessment and Management of the Patient with Chronic Cough

122 – Cystic Lung Disease

123 – Pulmonary Medicine- Additional Clinical Pearls and Take-Home Messages

124 – Updates in Stroke Diagnosis and Management

125 – Headache

126 – Seizure Disorders

127 – Neurology Q&A

128 – Autonomic Neuropathy

129 – Hot Topic in Neurology – Approach to Concussion

130 – Neurology Q&A

131 – Board Review in Neurology

132 – Movement Disorders

133 – Multiple Sclerosis

134 – AI Is Not Coming for Your Job – An Insider Industry Perspective

135 – End of Life – A Framework for Advance Care Planning Conversations

136 – Obesity – Focus on Weight Loss Medications

137 – General Internal Medicine and Primary Care Q&A

138 – Evaluation of Cardiac and Pulmonary Risk in the Preop Patient

139 – Treating Opioid Use Disorder

140 – Challenging General Internal Medicine Cases

141 – Hot Topic in General Internal Medicine – Cannabis in General Medicine

142 – General Internal Medicine and Primary Care Q&A

143 – General Internal Medicine Board Review

144 – Challenging Case Discussion – Message in a Bottle – A 43-yo Woman Presents to the Emergency Room

145 – Morning Report- Instructive Cases

146 – Workshop- General Internal Medicine Case Studies

147 – Update in Geriatrics

148 – Hyperlipidemia

149 – General Internal Medicine- Additional Clinical Pearls & Take Home Messages

150 – Sepsis and Septic Shock

151 – Cardiogenic Shock, CHF, and Malignant Arrhythmias

152 – Hot Topic in Critical Care – Palliative Care in the ICU

153 – Critical Care Q&A

154 – Mechanical Circulatory Support Devices

155 – Evidence-Based Preventative Therapy in the ICU

156 – Popular ICU Topics

157 – Respiratory Failure

158 – Critical Care Q&A

159 – Board Review in Critical Care

160 – Mechanical Ventilation- Basics to Advanced Concepts

161 – Optimizing the ABCDEF Bundle

162 – Best Practices for the Management of Severe COVID-19 Pneumonia

163 – Critical Care- Additional Clinical Pearls and Take-Hom Messages

164 – 2026 Diabetes Overview

165 – Diabetes – Managing Common Complications

166 – Overview of Transgender Care

167 – Endocrinology Q&A

168 – Thyroid Disease

169 – Hot Topic in Endocrinology – Advances in Diabetes Technology

170 – Calcium Cases

171 – Endocrinology Q&A

172 – Endocrine Board Review

173 – Challenging Case Discussion – A Missed Diagnosis

174 – Adrenal Disorders

175 – Pituitary Disorders

176 – Primary Care for Transgender and Gender Diverse People

177 – Testosterone Therapy in Men

178 – Endocrinology- Additional Clinical Pearls and Take-Home Messages

179 – Approach to Joint Pain

180 – Rheumatoid Arthritis – Diagnosis and New Treatment

181 – Rheumatology Q&A

182 – Vasculitis-GCA-PMR

183 – Spondyloarthritis, Including Psoriatic Arthritis

184 – Hot Topic in Rheumatology – Cardio-Rheumatology

185 – Rheumatology Q&A

186 – Rheumatology Board Review

187 – Update in Rheumatic Diseases – Scleroderma, Sjögren’s and Myositis

188 – Systemic Lupus Erythematosus and the Antiphospholipid Syndrome

189 – Osteoporosis

190 – Gout and CPPD Disease

191 – Rheumatology – Take-Home Messages and Clinical Pearls

192 – State of the Art – POCUS

193 – Biostatistics Board Review

194 – Update in Hospital Medicine

195 – Q&A

196 – Physician Wellness and Burnout – How to Prevent It

197 – On the Emergency Room’s Front Line

198 – Setting Your Leadership GPS – 5 Steps to Leading Yourself and Others to Extraordinary Outcomes

199 – Board Review Practice – 1

200 – Board Review Practice – 2

201 – Board Review Practice – 3

202 – Board Review Practice – 4

203 – Emerging Topics for the Boards – Bringing Health Equity

204 – Diagnostic Errors in Medicine

205 – Depression Update

206 – Dermatology

207 – 2026 Allergy and Immunology Overview and Update