Clinics in Reproductive Medicine and Assisted Reproductive Technology Volume 2 (PDF)

by B.N. Chakravarty

Volume 2 of the book Clinics in Reproductive Medicine and Assisted Reproductive Technology deals with more commonly encountered clinical topics in infertility practice like PCOS, endometriosis, uterine factors in female infertility, hyperprolactinemia and hypothyroidism in reproductive medicine and immunological factors in infertility and recurrent miscarriage. To make the presentations more specific and transparent, each chapter has been classified into subchapters for readers’ convenience of easy understanding. In current infertility practice, PCOS and endometriosis are two major problems. Attempt has been made to highlight the recent concepts and future thoughts about approach to management of these two intractable and perplexing gynecological disorders leading to infertility.Planning an ideal ovarian stimulation protocol for an individual patient is a critical step in IVF treatment care. From clinical experience, it is very apparent that ‘one-size fits all’ theory cannot be applied to all IVF patients for formulating their suitable stimulation regime. Rather it is essential to predetermine individual ovarian potential before embarking on the specific regime of ovarian stimulation. In addition, it is being speculated that all types of COS currently practiced may have an adverse impact on endometrial receptivity. Obviously, there is a gradual move towards the dictum ‘freeze all embryos transfer in next cycle’. These problems, their practical solutions and limitations have been elaborately discussed in different chapters dealing with controlled ovarian stimulation. In addition, the chapter on anti-mullerian hormone (AMH) adds further information of the background for the development of ‘personalized ovarian stimulation’ for each individual patient undergoing IVF treatment cycle. The individualized stimulation protocol for poorly responding women (low ovarian reserve) has already been incorporated in Volume 1 of the book.