Penn Medicine Penn Neuromuscular Symposium 2026

1. Overview
The annual Penn Neuromuscular Symposium is designed to provide clinicians with a comprehensive and practical update on the diagnosis and management of neuromuscular disorders. Through expert-led presentations and case-based discussions, attendees will learn how to approach a wide spectrum of neuromuscular diseases, interpret diagnostic studies, and apply current best practices in patient care. The course will also highlight recent advances in the field, including newly approved therapies and emerging innovations that are shaping the future of neuromuscular medicine.
Course Date: Saturday, March 21, 2026, 8:00 AM – 3:30 PM, Smilow Center, Rubenstein Auditorium, Philadelphia, PA
2. Learning Objectives

After completing this activity, participants should be able to:

Describe novel treatments for myasthenia gravis, including emerging therapies and their mechanisms of action.
Discuss new diagnostic approaches and treatment strategies for neuropathy associated with amyloidosis.
Discuss the different types of demyelinating neuropathies and outline current approaches to their diagnosis and management.
Describe novel treatments for spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS), including recently approved therapies and emerging clinical trial data.
Describe current approaches to the diagnosis and treatment of pulmonary complications in neuromuscular diseases.
Apply antibody testing in the diagnosis of inflammatory myopathies and describe novel therapies under investigation for their treatment.
Discuss the role and recent advances of gene therapy in the treatment of hereditary myopathies.
Discuss challenging clinical cases to enhance diagnostic reasoning and management strategies in neuromuscular disorders.
Discuss recent advances in the diagnosis and treatment of hereditary neuropathies.

3. Target Audience

Best for neurologists and neuromuscular specialists who want updates on gene therapies, myasthenia gravis treatments, and neuropathies.

4. Topics

Advances in Gene- and RNA-Targeted Therapies for SMA and ALS

Antibody Testing and Novel Therapies in Inflammatory Myopathies

Diagnosing and Managing Demyelinating Neuropathies

Hereditary Neuropathies, Including hATTR – New Insights and Treatments

How to Incorporate Novel Treatments in Myasthenia Gravis

Neuromuscular Case Presentation – 01

Neuromuscular Case Presentation

Welcome