The Guinea Pig Model: An Alternative Method For Vaccine Potency Testing (PDF)

by Viviana Parreño (Author)
 

This book summarizes the development and statistical validation of a guinea pig model as an alternative for potency testing of the viral antigens included in combined vaccines applied in cattle to control the respiratory, reproductive, and neonatal calf diarrhea syndromes. The model allows, in one serum sample, to test the vaccine quality for all the viral antigens included in aqueous as well as in oil-adjuvanted formulations of bovine vaccines. The methodology proposed for the control of bovine herpes virus, parainfluenza, and rotavirus were recommended by CAMEVET as guidelines for the 30 countries in the forum, including the US.
Key Features
Reviews combined vaccines used for cattleSummarizes animal models used for vaccine testingFocuses on bovine herpesviruses, rotaviruses, parainfluenza, and bovine viral diarrhea virusProvides guidance on the effectiveness of the Guinea Pig model for testing vaccine immunogenicity

Product Details

Publisher: CRC Press; April 10, 2023
Language: English
ISBN: 9780367489861
ISBN: 9781000850611