This book contains 300 multiple choice questions (MCQs), in the format of a single best answer (SBA) from four options, for undergraduate medical students preparing for the Duke Elder prize exam run by the Royal College of Ophthalmologists (RCOphth) annually.The content is organised in line with topics drawn from the candidate information pack provided by the RCOphth. Each question is supplemented with a detailed explanation of the right answer as well as explanations for the alternative answers, elucidating common mistakes made by students. These explanations are supplemented with schematic diagrams which greatly aid understanding. There are 8 chapters focusing on topics outlined in the Duke Elder exam, each containing a set of 25 questions and answers. This allows us to cover the most commonly seen topics appearing in the exam.The book will also provide a full mock assessment which will offer a unique opportunity for candidates to apply their knowledge in an exam context. The exam format is such that candidates must complete 90 MCQs in the space of 2 hours. Our mock will provide candidates with a 100 MCQ mock to be completed in the space of 2 hours 15 minutes.